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By Alton Meister

Advances in Enzymology and comparable parts of Molecular Biology is a seminal sequence within the box of biochemistry, providing researchers entry to authoritative reports of the most recent discoveries in all parts of enzymology and molecular biology. those landmark volumes date again to 1941, offering an unequalled view of the old improvement of enzymology. The sequence bargains researchers the most recent realizing of enzymes, their mechanisms, reactions and evolution, roles in advanced organic strategy, and their software in either the laboratory and undefined. each one quantity within the sequence good points contributions by way of best pioneers and investigators within the box from world wide. All articles are rigorously edited to make sure thoroughness, caliber, and clarity.

With its wide variety of themes and lengthy ancient pedigree, Advances in Enzymology and comparable parts of Molecular Biology can be utilized not just by means of scholars and researchers in molecular biology, biochemistry, and enzymology, but in addition via any scientist drawn to the invention of an enzyme, its homes, and its functions.

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Analogies are easy to find among the model enzymes, since the activity of many catalysts may be enhanced by traces of metallic activators (for example the effect of traces of iron in the activation of charcoal (162)). This could very well be the role of metals such as Ca and Mg in proteolytic enzymes and of A1 and Zn in the metal phthalocyanines. “The energy term of the second electron of Mg for instance, is at the same level as the higher filled electron band, which opens the possibility that this ion takes over an electron from the protein making its band unsaturated and conductant.

Trans. , 42, 155 (1946). 6, 319 (1952). 16. Bayliss, N. , Quart. Revs. (London), 17. ,Revs. Mod. , 17,61 (1945). 18. , Biochem. J . , 68,694 (1952). 19. Bickel, A. ,and Kooyman, E. , Nature, 170,212(1952). MECHANIBM OF ENZYMIC OXIDOREDUCTlON 43 20. Bonnischen, R. , Scand. Chim. Acta, 1,685 (1947). 21. ,J . Am. Chem. ,79, 1040 (1950). 22. , Chem. Weekblad, 47,948(1951). 23. ,and Gorin, M. , J . Am. Chem. ,64,2124(1932). 24. , 41, 752 (1908). 25. , Bwchem. , 982, 88 (1935). 26. Bremner, J. , Research (London),1, 281 (1948).

Chem. ,73,183 (1951). 142. , in The Valences of the Transition Elements, Victor Henri Memorial Volume, Desoer, LiQe, 1948. 143. , in Haemoglobin, Barcroft Memorial Conference, Butterworth, London, 1949, p. 67; Interscience, New York. 144. , Corey, R. , and Branson, H. , Proc. Natl. Acad. Sci. U . , sr, 205 (1951). 145. , Proc. Natl. Acad. Sci. U . , 22, 159 (1936). 146. Posner, A. , Trans. ,49,389 (1953). 147. Potter, V. , Cancer Research, 9,358 (1943). 148. Potter, V. , in Advances in Enzymology, Vol.

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