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Content material: Foreword, web page ixAbbreviations and emblems, Pages x-xiIntroduction, Pages 1-4II - Graphical abstracts of response numbers, Pages 5-21RXN1 - Cross-Coupling of Organometallics with RX Derivatives, Pages 23-47RXN2 - Cross-Coupling of Organometallics with RCOX Derivatives, Pages 48-52RXN3 - Cross-Coupling of Siloxycyclopropanes with RX and RCOX Derivatives, Pages 53-54RXN4 - Cross-Coupling of Terminal Alkynes with RX Derivatives, Pages 55-60RXN5 - Intermolecular HECK response, Pages 61-71RXN6 - Intramolecular HECK response, Pages 72-79RXN7 - Intramolecular Coupling of Di(Vinyl Halides), Pages 80-81RXN8 - Tandem HECK-Anion seize technique of Alkenes, Alkynes, Allenes and Dienes, Pages 82-85RXN9 - Tandem HECK-Anion seize technique of Norbornene and similar Compounds, Pages 86-88RXN10 - Tandem Arylsulfonation-Cyclization method, Pages 89-90RXN11 - Tandem Cyclization-Anion catch (-Carbonylation) means of Alkenes, Allenes and Alkynes, Pages 91-94RXN12 - Tandem Cyclization-Anion-Capture means of Ene-Vinyl, Ene-Aryl and Ene-Alkyl Halides, Pages 95-98RXN13 - 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Telomerization of 1,3-Dienes with Nucleophiles, Pages 228-231RXN56 - WACKER strategy, Pages 232-234RXN57 - training of Ketones from Alcohols or Derivatives through a β-Hydride removing, Pages 235-237RXN58 - education of α,β-Unsaturated Carbonyl Derivatives through a β-Hydride removal, Pages 238-240RXN59 - instruction of α-Diketones Derivatives through an Oxidative Rearrangement of a Propargyl Acetate, Pages 241-242RXN60 - Carbonylation, Pages 243-252RXN61 - Isomerization of Alkynes, Pages 253-255RXN62 - Addition of Thiols to Alkynes, Pages 256-257RXN63 - instruction of Allylic Acetates from Alkynes by means of Tandem Redox-Addition, Pages 258-259RNX64 - Tandem Cyclization-Capture strategy of Enynes, Pages 260-261RXN65 - Aldol-Like Condensation of Enol Esters with Aldehydes, Pages 262-263RXN66 - Addition of Fluoroalkyl lodides to Alkenes or Alkynes through a Pd(I) Species, Pages 264-265RXN67 - Intermolecular Tandem Carbonylation-Coupling-Cyclization technique of Aryl Halides with Terminal Alkynes, Pages 266-267RXN68 - 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1,3-Butadien-2-ylaminocyclization of Allenyl Tosylcarbamates, Pages 296-297RXN82 - Addition of Pronucleophiles on Aldehydes, Pages 298-300RXN83 - Allylation of Pronucleophiles with Allylstannanes, Pages 301-302RXN84 - Cross-Coupling Carbonylation of Aryl lodides with 5-membered Cyclic Olefins, Pages 303-304This web page is deliberately left clean, web page 305

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Extra resources for Analytical Profiles of Drug Substances, Vol. 13

Sample text

1 . . 1 . . 1 . . 1 . . 1 ' . . 110 , * 8B 70 60 Fig. 4. 5 0 fPM(b) 44 44 20 PMR spectrum of camphor in CDCl 3' 0 40 J A B E R S . M O S S A A N D M A H M O U D M . A . HASSAN Table 4. PMR C h a r a c t e r i s t i c s o f Camphor Group Methylene a t ( C-2, Chemical s h i f t (ppm) C-4 and C-5 ) . 43 b t and Methine a t C-3 p r o t o n s . 83 s C-10 M e s = singlet ; t = t r i p l e t ; b t = b r o a d t r i p l e t ; rn = m u l t i p l e t . Our assignment o f t h e methyl p r o t o n s s i n g l e t s i s b a s e d on t h e a n i s o t r o p y of t h e c a r b o n y l f u n c t i o n o f camphor.

Camphor wooddisti//ationpost. A . Retod("Koshiki"). Kettk . C. 1st condenser. D . nndcondenser. E . 3rd condenser. E Liebiy condenser. A p e Foor,rerumofdistr'ilatlonwater. ( r o h ~ b r h o nw r r h r p i p c ) . F i g u r e 9. so JABER S. MOSSA AND MAHMOUD M. A . HASSAN 50Y, Crudekmphor (Recovered Camphor) o r “0” Ca (T( p hor 46% campior oil or Bppmduct oil (Dccanphorlzed (Oil) (Sublimcltion) Refined Camphor(2nd class) or “00“ Camphor I (Sublimution and Pressing) Refined Camphor(f St class) O r “A“ Camphor Figure 1 0 .

Kettk . C. 1st condenser. D . nndcondenser. E . 3rd condenser. E Liebiy condenser. A p e Foor,rerumofdistr'ilatlonwater. ( r o h ~ b r h o nw r r h r p i p c ) . F i g u r e 9. so JABER S. MOSSA AND MAHMOUD M. A . HASSAN 50Y, Crudekmphor (Recovered Camphor) o r “0” Ca (T( p hor 46% campior oil or Bppmduct oil (Dccanphorlzed (Oil) (Sublimcltion) Refined Camphor(2nd class) or “00“ Camphor I (Sublimution and Pressing) Refined Camphor(f St class) O r “A“ Camphor Figure 1 0 . 51 CAMPHOR where camphor w i l l sublime i n p u r e s t a t e (56,57).

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